CDK2/Bcl2-IN-1
CAT:
804-HY-149436
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK2/Bcl2-IN-1
- UNSPSC Description: CDK2/Bcl2-IN-1 (compound 1), a saponin and a CDK-2 inhibitor (IC50=117.6 nM) with promising cytotoxicity against cancer cells. CDK2/Bcl2-IN-1 also inhibits Bcl-2, and induces apoptosis in A549 lung cancer cells[1].
- Target Antigen: CDK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: cancer
- Assay Protocol: https://www.medchemexpress.com/cdk2-bcl2-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: CC1=CC[C@@]2(C(O[C@@H]3[C@@H](OS(=O)(O)=O)[C@H](O)[C@H](O)CO3)=O)CC[C@@]4(C)[C@]5(C)CCC6C(C)(C)[C@@H](O)CC[C@]6(C)C5CCC4C2[C@H]1C
- Molecular Weight: 668.88
- References & Citations: [1]Eltamany EE, et al. A New Saponin (Zygo-albuside D) from Zygophyllum album Roots Triggers Apoptosis in Non-Small Cell Lung Carcinoma (A549 Cells) through CDK-2 Inhibition. ACS Omega. 2023 Aug 8;8(33):30630-30639.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported