CDK2-IN-9
CAT:
804-HY-144811
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK2-IN-9
- CAS Number: 2919216-33-2
- UNSPSC Description: CDK2-IN-9 is a potent CDK2 inhibitor with an IC50 of 0.63 μM. CDK2-IN-9 shows antiproliferative activity. CDK2-IN-9 induces apoptosis and cell cycle arrest at S and G2/M phase. CDK2-IN-9 has the potential for the research of melanoma[1].
- Target Antigen: Apoptosis; CDK
- Type: Reference compound
- Related Pathways: Apoptosis;Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/cdk2-in-9.html
- Solubility: 10 mM in DMSO
- Smiles: O=S(C1=CC=C(Cl)C=C1)(NN2C(COC3=CC=CC=C3)=NC4=C(C=CC=C4)C2=O)=O
- Molecular Weight: 441.89
- References & Citations: [1]Mohammed ER, et al. Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma. J Enzyme Inhib Med Chem. 2022 Dec;37(1):686-700.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported