Metallo-β-lactamase-IN-4

Metallo-β-lactamase-IN-4

• CAS Number: 2711044-25-4
• UNSPSC Description: Metallo-β-lactamase-IN-4 (compound 40) is a potent metallo-β-lactamases (MBL) inhibitor, with IC50 values of 0.5 μM (VIM-1), 2.1 μM (NDM-1), and 3.3 μM (IMP-7), respectively[1].
• Target Antigen: Bacterial; Beta-lactamase
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/metallo-β-lactamase-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=C(S(=O)(NC(N)=N)=O)C=C1)CCS
• Molecular Weight: 302.37
• References & Citations: [1]Kaya C, et al. N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases. J Med Chem. 2022 Mar 10;65(5):3913-3922.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported