Anti-Histone H2B Rabbit Monoclonal Antibody

Anti-Histone H2B Rabbit Monoclonal Antibody

• Description: Boster Bio Anti-Histone H2B Rabbit Monoclonal Antibody catalog # M11068. Tested in WB, IHC, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
• Synonyms: Histone H2B type 1-K;H2B K;HIRA-interacting protein 1;HIST1H2BK;H2BFT, HIRIP1;
• CAS Number: 9007-83-4
• Gene Name: Histone H2B type 1-K
• UniProt: O60814
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: A synthesized peptide derived from human Histone H2B
• Clonality: Monoclonal
• Clone: Clone: HAD-8
• Tissue Specificity: Highly expressed in skeletal muscle, heart, liver and testis. .
• Applications: WB,IHC,ICC,IF,IP,Flow Cytometry
• Purification: Affinity-chromatography
• Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
• Form: Liquid
• Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
• Components: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
• Storage Conditions: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
• Calculated Molecular Weight: 13890 MW
• Observed Molecular Weight: 17 kDa
• Fragment: Rabbit IgG
• Applications Notes: WB 1:5000-1:20000
  IHC 1:50-1:200
  ICC/IF 1:50-1:200
  IP 1:30
  FC 1:50
• Subcellular Location: Nucleus. Chromosome.
• Protein Name: T-cell surface glycoprotein CD3 zeta chain