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Anti-Histone H2A.X H2AFX Rabbit Monoclonal Antibody

CAT:
519-M00241-1
Size:
100 µL
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Anti-Histone H2A.X H2AFX Rabbit Monoclonal Antibody - image 1

Anti-Histone H2A.X H2AFX Rabbit Monoclonal Antibody

  • Description: Boster Bio Anti-Histone H2A.X H2AFX Rabbit Monoclonal Antibody catalog # M00241-1. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.
  • Synonyms: Histone H2AX;H2a/x;Histone H2A.X;H2AFX;H2AX;
  • CAS Number: 9007-83-4
  • Gene Name: Histone H2AX
  • UniProt: P16104
  • Host: Rabbit
  • Reactivity: Human,Mouse,Rat
  • Immunogen: A synthesized peptide derived from human Histone H2A.X
  • Clonality: Monoclonal
  • Clone: Clone: BIA-8
  • Tissue Specificity: Ubiquitous. The mRNA is present at similar levels in viable and apoptotic cells, whereas the protein is dramatically highly expressed in apoptotic cells.
  • Applications: WB,IHC,ICC,IF,IP
  • Purification: Affinity-chromatography
  • Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
  • Form: Liquid
  • Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
  • Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation. .
  • Components: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
  • Storage Conditions: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
  • Calculated Molecular Weight: 15145 MW
  • Observed Molecular Weight: 100-110 kDa
  • Fragment: Rabbit IgG
  • Applications Notes: WB 1:500-1:2000
    IHC 1:50-1:200
    ICC/IF 1:50-1:200
    IP 1:50
  • Subcellular Location: Nucleus . Chromosome .
  • Protein Name: P2X purinoceptor 1