Anti-Histone H3 HIST1H3A Rabbit Monoclonal Antibody

Anti-Histone H3 HIST1H3A Rabbit Monoclonal Antibody

• Description: Boster Bio Anti-Histone H3 HIST1H3A Rabbit Monoclonal Antibody catalog # M12477-10. Tested in WB, IHC, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.
• Synonyms: Histone H3.1;Histone H3/a;Histone H3/b;Histone H3/c;Histone H3/d;Histone H3/f;Histone H3/h;Histone H3/i;Histone H3/j;Histone H3/k;Histone H3/l;HIST1H3A;H3FA;HIST1H3B;H3FL;HIST1H3C;H3FC;HIST1H3D;H3FB;HIST1H3E;H3FD;HIST1H3F;H3FI;HIST1H3G;H3FH;HIST1H3H;H3FK;HIST1H3I;H3FF;HIST1H3J;H3FJ;
• CAS Number: 9007-83-4
• Gene Name: Histone H3.1
• UniProt: P68431
• Host: Rabbit
• Reactivity: Human,Mouse,Rat
• Immunogen: A synthesized peptide derived from human Histone H3
• Clonality: Monoclonal
• Clone: Clone: HDE-8
• Tissue Specificity: Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney. .
• Applications: WB,IHC,ICC,IF
• Purification: Affinity-chromatography
• Concentration: Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
• Form: Liquid
• Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
• Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
• Components: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
• Storage Conditions: Store at -20℃ for one year. For short term storage and frequent use, store at 4℃ for up to one month. Avoid repeated freeze-thaw cycles.
• Calculated Molecular Weight: 15404 MW
• Observed Molecular Weight: 15 kDa
• Fragment: Rabbit IgG
• Applications Notes: WB 1:1000-1:2000
  IHC 1:1000-1:2000
  ICC/IF 1:1000-1:2000
• Subcellular Location: Nucleus. Chromosome.
• Protein Name: T-cell surface glycoprotein CD3 zeta chain