A1AR antagonist 3

A1AR antagonist 3

• CAS Number: 2413257-73-3
• UNSPSC Description: A1AR antagonist 3 (compound 13) is a selective adenosine 1 (A1) receptor antagonist with Kis of 9.69 nM and 0.529 nM for human A1 and rat A1, respectively. A1AR antagonist 3 can be used for researching neurological diseases[1].
• Target Antigen: Adenosine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/a1ar-antagonist-3.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=C(C=C1)C(NC2=NC(C3=CC=CC=C3)=C(S2)C(C4=CC=C(C=C4)C)=O)=O
• Molecular Weight: 428.50
• References & Citations: [1]Abdelrahman A, et al. Substituted 4-phenylthiazoles: Development of potent and selective A1, A3 and dual A1/A3 adenosine receptor antagonists. Eur J Med Chem. 2020;186:111879.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported