NF-κB/PON1-IN-1
CAT:
804-HY-146058
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NF-κB/PON1-IN-1
- CAS Number: 2419107-97-2
- UNSPSC Description: NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 µM) and hepatoprotective activities[1].
- Target Antigen: NF-κB; Reactive Oxygen Species
- Type: Reference compound
- Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/nf-κb-pon1-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(NC1=NC=CN=C1)CSC(N2C3=CC=C(S(=O)(N)=O)C=C3)=NC4=C(C=CC=C4)C2=O
- Molecular Weight: 468.51
- References & Citations: [1]Soliman AM, et al. Antioxidant activity of novel quinazolinones bearing sulfonamide: Potential radiomodulatory effects on liver tissues via NF-κB/ PON1 pathway. Eur J Med Chem. 2020 Jul 1;197:112333.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported