NF-κB-IN-1
CAT:
804-HY-138537-04
Size:
10 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NF-κB-IN-1
- CAS Number: 1227098-15-8
- UNSPSC Description: NF-κB-IN-1, a 4-arylidene crucumin analogue, is a potent NF-κB signaling pathway inhibitor. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells[1].
- Target Antigen: IKK
- Type: Reference compound
- Related Pathways: NF-κB
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/nf-κb-in-1.html
- Smiles: O=C(/C=C/C(C=C1)=CC(OC)=C1OC)/C(C(/C=C/C(C=C2)=CC(OC)=C2OC)=O)=C/C(C=C3)=CC(OC)=C3O
- Molecular Weight: 530.57
- References & Citations: [1]Qiu X, et, al. Synthesis and identification of new 4-arylidene curcumin analogues as potential anticancer agents targeting nuclear factor-κB signaling pathway. J Med Chem. 2010 Dec 9;53(23):8260-73.
- Shipping Conditions: Blue Ice