NF-κB-IN-1

NF-κB-IN-1

• CAS Number: 1227098-15-8
• UNSPSC Description: NF-κB-IN-1, a 4-arylidene crucumin analogue, is a potent NF-κB signaling pathway inhibitor. NF-κB-IN-1 directly inhibits IKK to block NF-κB activation. NF-κB-IN-1 effectively inhibits the viability of lung cancer cells and attenuates the clonogenic activity of A549 cells[1].
• Target Antigen: IKK
• Type: Reference compound
• Related Pathways: NF-κB
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/nf-κb-in-1.html
• Smiles: O=C(/C=C/C(C=C1)=CC(OC)=C1OC)/C(C(/C=C/C(C=C2)=CC(OC)=C2OC)=O)=C/C(C=C3)=CC(OC)=C3O
• Molecular Weight: 530.57
• References & Citations: [1]Qiu X, et, al. Synthesis and identification of new 4-arylidene curcumin analogues as potential anticancer agents targeting nuclear factor-κB signaling pathway. J Med Chem. 2010 Dec 9;53(23):8260-73.
• Shipping Conditions: Blue Ice