Carbonic anhydrase inhibitor 7

Carbonic anhydrase inhibitor 7

• CAS Number: 546105-61-7
• UNSPSC Description: Carbonic anhydrase inhibitor 7 (compound 5b) is a potent inhibitor of human carbonic anhydrase (hCA), with Kis of 6.5 nM, 7.1 nM, 72.1 nM, and 255.8 nM for hCA IX, hCA II, hCA XII and hCA I, respectively[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-7.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC(C2=CC=C(OCO3)C3=C2)=NC4=CC=CC=C14)NC5=CC=C(S(=O)(N)=O)C=C5
• Molecular Weight: 447.46
• References & Citations: [1]Swain B, et, al. Exploration of 2-phenylquinoline-4-carboxamide linked benzene sulfonamide derivatives as isoform selective inhibitors of transmembrane human carbonic anhydrases. Eur J Med Chem. 2022 Apr 15;234:114247.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported