Carbonic anhydrase inhibitor 20

Carbonic anhydrase inhibitor 20

• UNSPSC Description: Carbonic anhydrase inhibitor 20 (compound 11) is an inhibitor of piperazinosulfonamide carbonic anhydrase (Carbonic Anhydrase). The Ki of Carbonic anhydrase inhibitor 20 for hCA I, hCA II, hCA IX, and hCA XII are 47.6 nM, 36.5 nM, 8.3 nM, and 2.7 nM respectively[1].
• Target Antigen: Carbonic Anhydrase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-20.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1CCC(C(N2CCN(CC3=CC=CC=C3)CC2)=O)CC1)C4=CC=C(S(N)(=O)=O)C=C4
• Molecular Weight: 470.58
• References & Citations: [1]Moi D, et al. Discovery of a New Class of 1-(4-Sulfamoylbenzoyl)piperidine-4-carboxamides as Human Carbonic Anhydrase Inhibitors. ACS Med Chem Lett. 2024 Mar 13;15(4):470-477.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported