PCSK9 modulator-2
CAT:
804-HY-128334
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PCSK9 modulator-2
- CAS Number: 2365416-53-9
- UNSPSC Description: PCSK9 modulator-2 (Compound 1) is a potent modulator of PCSK9 with an EC50 value of 202 nM. PCSK9 is a recently validated target for lowering low-density lipoprotein cholesterol (LDL-C). PCSK9 modulator-2 has the potential for the research of hyperlipidemia[1].
- Target Antigen: PCSK9
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/pcsk9-modulator-2.html
- Solubility: 10 mM in DMSO
- Smiles: FC1=CC=CC2=C1NC=C2CC3=CC4=CC(F)=CC=C4N3
- Molecular Weight: 282.29
- References & Citations: [1]Xie H, et al. From methylene bridged diindole to carbonyl linked benzimidazoleindole: Development of potent and metabolically stable PCSK9 modulators. Eur J Med Chem. 2020 Nov 15;206:112678.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported