PCSK9-IN-2

PCSK9-IN-2

• CAS Number: 2099167-44-7
• UNSPSC Description: PCSK9-IN-2 is a novel small molecule inhibitor of PCSK9-LDLR protein–protein interaction (PPI) with an IC50 value of 7.57 μM.
• Target Antigen: PCSK9
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Neuroscience-Neuromodulation
• Field of Research: Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/pcsk9-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1NCCCC[C@H]1N[C@@H]2CC(N(C2=O)C3=CC=C(C=C3)N4C(C[C@H](C4=O)N[C@@H]5CCCCNC5=O)=O)=O
• Molecular Weight: 524.57
• References & Citations: [1]Sun H, et al. Discovery of Novel Small Molecule Inhibitors Disrupting the PCSK9-LDLR Interaction. J Chem Inf Model. 2021 Oct 25;61(10):5269-5279.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported