STAT6 Polyclonal Antibody

STAT6 Polyclonal Antibody

• Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
• Synonyms: 12S1644,D12S1644,IL 4 STAT,IL-4 Stat,IL4 STAT,Interleukin 4 Induced,Interleukin 4 Induced Transcription Factor IL4 STAT,Signal transducer and activator of transcription 6,Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced,Signal Transducer And Activator Of Transcription 6 Nirs Variant 1,Signal transducer and activator of transcription 6,interleukin 4 induced,STAT 6,STAT interleukin4 induced,STAT,interleukin4 induced,Stat6,STAT6,STAT6B,STAT6C,Transcription factor IL 4 STAT
• CAS Number: 9007-83-4
• Swiss Prot: P42226
• Accession Number: BC075852
• Host: Rabbit
• Reactivity: Human,Mouse
• Immunogen: Recombinant protein of human STAT6
• Clonality: Polyclonal
• Isotype: IgG
• Conjugation: Unconjugated
• Applications: WB,ELISA
• Purification: Affinity purification
• Concentration: 0.2 mg/mL
• Dilution: WB 1:500-1:2000
• Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
• Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
• Calculated Molecular Weight: 94 kDa