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STAT6 Polyclonal Antibody

CAT:
866-RD265706A-03
Size:
200 µL
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
STAT6 Polyclonal Antibody - image 1

STAT6 Polyclonal Antibody

  • Background: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.
  • Synonyms: D12S1644,IL-4-STAT,STAT6B,STAT6C,STAT6
  • CAS Number: 9007-83-4
  • Gene ID: 6778
  • Swiss Prot: P42226
  • Host: Rabbit
  • Reactivity: Human,Mouse,Rat
  • Immunogen: Recombinant fusion protein of human STAT6 (NP_001171550.1).
  • Isotype: IgG
  • Conjugation: Unconjugated
  • Applications: WB
  • Purification: Affinity purification
  • Concentration: 1 mg/mL
  • Dilution: WB 1:500-1:2000
  • Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
  • Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
  • Calculated Molecular Weight: 74 kDa/81 kDa/94 kDa
  • Observed Molecular Weight: 110 kDa