Monoclonal Anti-Human CD28 Antibody, premium grade

Monoclonal Anti-Human CD28 Antibody, premium grade

• Background: T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
• Description: Monoclonal Anti-Human CD28 Antibody, premium grade (CD8-M120b) is recombinantly produced from human 293 cells (HEK293).
• CAS Number: 9007-83-4
• Host: HEK 293
• Origin Species: Mouse
• Target: CD28
• Conjugation: Unconjugated
• Tag: Mouse IgG1 | Mouse Kappa
• Stability: 2-8°C for 12 months under sterile condition; -70°C for 24 months._x000D_For long term storage, the product should be stored at liquid state at -70°C.
• Endotoxin: 0.002 EU per μg
• Purity: 95%
• Bioactivity: Immobilized Human / Cynomolgus / Rhesus macaque CD28, His Tag at 2 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CD28 Antibody, premium grade (Cat. No. CD8-M120b) with a linear range of 0.098-1.563 ng/mL (QC tested).
• Format: Liquid
• Buffer: PBS, pH7.4
• Additives: Trehalose
• Shipping Conditions: Dry Ice
• Storage Conditions: -70°C