Mouse Anti-Human CD28 Monoclonal Antibody
CAT:
209-101-M301
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mouse Anti-Human CD28 Monoclonal Antibody
- Description: CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD28 and CTLA-4 are structurally homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Mouse CD28 is expressed constitutively on virtually 100% of mouse Tcells and on developing thymocytes.
- Synonyms: CD28; Tp44
- CAS Number: 9007-83-4
- NCBI Gene ID: 940
- UniProt: P10747
- Accession Number: NP_001230007.1
- Accession Number mRNA: NM_001243078.1
- Gene Location: 2q33
- Host: Mouse
- Origin Species: Human
- Species Reactivity: Human
- Target Antigen: Human Recombinant CD28 EC domain
- Isotype: IgG1
- Clone: (#12B3)
- Validated Applications: WB, FC
- Purification Method: Protein G chromatography
- Activity: Stimulation
- Form: Lyophilized
- Buffer: PBS
- Reconstitution: Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
- Shipping Conditions: Room Temperature
- Storage Conditions: Lyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.