BCR-ABL1-IN-1
CAT:
804-HY-145887-02
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
BCR-ABL1-IN-1
- CAS Number: 1488090-21-6
- UNSPSC Description: BCR-ABL1-IN-1 is a potent, orally active, and specific inhibitor of ABL kinase. BCR-ABL1-IN-1 has potential for elucidating the role of ABL kinases in the brain in non-clinical studies[1].
- Target Antigen: Bcr-Abl
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: Neuroscience-Neuromodulation
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/bcr-abl1-in-1.html
- Solubility: DMSO : 175 mg/mL (ultrasonic)
- Smiles: O=C(C1=CN=CC(C2=CC=CN=C2)=C1)NC3=CC=C(C=C3)OC(F)(F)F
- Molecular Weight: 359.30
- References & Citations: [1] Manley PW, et al. A kinase inhibitor which specifically targets the ABL myristate pocket (STAMP), but unlike asciminib crosses the blood-brain barrier. Bioorg Med Chem Lett. 2022;59:128577.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported