Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag™, premium grade

Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag™, premium grade

• Background: T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.
• Description: Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade (CD8-BM225) is recombinantly produced from human 293 cells (HEK293).
• CAS Number: 9007-83-4
• Host: HEK 293
• Origin Species: Mouse
• Target: CD28
• Conjugation: Biotin-labeled
• Tag: Mouse IgG1 & Avi | Mouse Kappa
• Stability: 2-8°C for 12 months under sterile condition; -70°C for 24 months._x000D_For long term storage, the product should be stored at liquid state at -70°C.
• Endotoxin: 0.002 EU per μg
• Purity: 95%
• Bioactivity: Immobilized Biotinylated Anti-Human CD28 Antibody, Mouse IgG1,Avitag, premium grade (Cat. No. CD8-BM225) at 1 μg/mL (100 μL/well) on streptavidin (Cat. No. STN-N5116) precoated (0.5 μg/well) plate can bind Human / Cynomolgus / Rhesus macaque CD28, His Tag with a linear range of 0.2-1 ng/mL (QC tested).
• Format: Liquid
• Buffer: PBS, pH7.4
• Additives: Trehalose
• Shipping Conditions: Dry Ice
• Storage Conditions: -70°C