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Cynomolgus Glypican 3 / GPC3 Protein, Llama IgG2b Fc Tag, low endotoxin

CAT:
716-GP3-C5259-100ug
Size:
100 µg
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Cynomolgus Glypican 3 / GPC3 Protein, Llama IgG2b Fc Tag, low endotoxin - image 1
Cynomolgus Glypican 3 / GPC3 Protein, Llama IgG2b Fc Tag, low endotoxin - image 2
Cynomolgus Glypican 3 / GPC3 Protein, Llama IgG2b Fc Tag, low endotoxin - image 3
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Cynomolgus Glypican 3 / GPC3 Protein, Llama IgG2b Fc Tag, low endotoxin

  • Background: Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
  • Description: Cynomolgus Glypican 3, Llama IgG2b Fc Tag, low endotoxin (GP3-C5259) is expressed from human 293 cells (HEK293). It contains AA Gln 25 - His 559 (Accession # XP_005594665.1).
  • Specifications: This protein carries a llama IgG2b Fc tag at the C-terminus. This protein contains a furin-like convertase cleavage site, 355-RQYR-358, and will be partially processed into N and C-terminal fragment with calculated MW of 38.1 kDa and 50.5 kDa respectively. The protein migrates as 40 kDa, 60 kDa and 100-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Expression Region: Gln 25 - His 559
  • Host: HEK 293
  • Target: Glypican 3
  • Conjugation: Unconjugated
  • Tag: C-LlamaFc(LlamaIgG2b)
  • Source: Cynomolgus
  • Stability: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Endotoxin: 0.01 EU per μg
  • Purity: 90%
  • Bioactivity: Immobilized Cynomolgus Glypican 3 Protein, Llama IgG2b Fc Tag (Cat. No. GP3-C5259) at 1 μg/mL (100 μL/well) can bind Anti-hGPC3 antibody, Human IgG1 with a linear range of 0.5-8 ng/mL (QC tested).
  • Format: Powder
  • Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
  • Additives: Trehalose
  • Molecular Weight: 38.1 kDa and 50.5 kDa
  • Shipping Conditions: Room Temperature
  • Storage Conditions: -20°C