Glypican-3/GPC3, Cynomolgus (HEK293, His)
CAT:
804-HY-P72628-02
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

Glypican-3/GPC3, Cynomolgus (HEK293, His)
- UNSPSC Description: GPC3 is a member of the heparan sulfate proteoglycans (HSPGs), and attaches to the cell surface by a glycosylphosphatidylinositol anchor. GPC3 is overexpressed in hepatocellular carcinoma (HCC) and can be used as a tumor marker for HCC. Membrane GPC3 can interact with several growth factors to promote the binding of growth factors to their receptors. GPC3 can form a complex with Wnt and activates Wnt signaling, leading to the HCC growth. In addition, GPC3 is also involved in the pathogenesis of Simpson-Golabi-Behmel overgrowth syndrome, regulates cell growth, regulates embryonic and fetal development[1][2][3]. Glypican-3/GPC3 Protein, Cynomolgus (HEK293, His) is the recombinant Cynomolgus-derived Glypican-3/GPC3 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Glypican-3/GPC3 Protein, Cynomolgus (HEK293, His) is 535 a.a., with molecular weight of 38 & 65-120 kDa, respectively.
- Type: Recombinant Proteins
- Assay Protocol: https://www.medchemexpress.com/cytokines/glypican-3-gpc3-protein-rhesus-macaque-hek293-his.html
- Purity: 95.0
- Smiles: QPPPPPPDAT CHQVRSFFQR LQPGLKWVPE TPVPGSDLQV CLPKGPTCCS RKMEEKYQLT ARLNMEQLLQ SASMELKFLI IQNAAVFQEA FEIVVRHAKN YTNAMFKNNY PSLTPQAFEF VGEFFTDVSL YILGSDINVD DMVNELFDSL FPVIYTQLMN PGLPDSALDI NECLRGARRD LKVFGNFPKL IMTQVSKSLQ VTRIFLQALN LGIEVINTTD HLKFSKDCGR MLTRMWYCSY CQGLMMVKPC GGYCNVVMQG CMAGVVEIDK YWREYILSLE ELVNGMYRIY DMENVLLGLF STIHDSIQYV QKNAGKLTTT IGKLCAHSQQ RQYRSAYYPE DLFIDKKVLK VAHVEHEETL SSRRRELIQK LKSFISFYSA LPGYICSHSP VAENDTLCWN GQELVERYSQ KAARNGMKNQ FNLHELKMKG PEPVVSQIID KLKHINQLLR TMSVPKGRVL DKNLDEEGFE SGDCGDDEDE CIGGSGDGMM KVKNQLRFLA ELAYDLDVDD VPGNNQQATP KDNEISTFHN LGNVH
- Molecular Weight: 38&65-120 kDa
- Shipping Conditions: Blue Ice
- Storage Conditions: Stored at -20°C for 2 years