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Anti-Bcl-X (Apoptosis Marker)(BCL2L1/2406), CF640R conjugate

CAT:
37-BNC402406-100
Size:
100 µL
Price:
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For price, please contact [email protected]
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Anti-Bcl-X (Apoptosis Marker)(BCL2L1/2406), CF640R conjugate - image 1
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Anti-Bcl-X (Apoptosis Marker)(BCL2L1/2406), CF640R conjugate

  • Description: Bcl-x belongs to the Bcl-2 family of proteins and plays a crucial role in apoptosis. Bcl-X has two isoforms: Bcl-XL (long), a 26 kDa protein which suppresses cell death, and Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2 and promotes apoptosis. This MAb reacts with both Bcl-XS and Bcl-XL proteins, and shows no cross-reaction with Bcl-2 or Bax proteins.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Synonyms: Bcl-x; Bcl-2-like protein 1; BCL2L1; Apoptosis regulator Bcl-X
  • CAS Number: 9007-83-4
  • UNSPSC: 41116161
  • UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
  • Gene Name: BCL2L1
  • Gene ID: 598
  • NCBI Gene ID: 516966
  • UniProt: Q07817
  • Cellular Locus: Cytoplasmic|Endoplasmic reticulum|Mitochondria
  • Host: Mouse
  • Species Reactivity: Human
  • Immunogen: Recombinant human BCL2L1 protein fragment (around aa 1-135) (exact sequence is proprietary)
  • Target Antigen: Bcl-x
  • Clonality: Monoclonal
  • Isotype: IgG
  • Clone: BCL2L1/2406
  • Conjugation: CF640R
  • Source: Animal
  • Applications: IHC, FFPE (verified)
  • Validated Applications: IHC, FFPE
  • Field of Research: Apoptosis, Cancer
  • Positive Control: Jurkat, K562, HL-60, or HeLa Cells. Reed-Sternberg cells in Hodgkin's lymphoma.
  • Concentration: 0.1 mg/mL
  • Buffer: PBS, 0.1% BSA, 0.05% azide
  • Molecular Weight: 27 kDa
  • Additionnal Information: ELISA: For coating use Ab at 1-5 ug/mL, order Ab without BSA; Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
  • Shipping Conditions: Room temperature
  • Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
  • Shelf Life: 2 years

Datasheet

MSDS