Anti-Bcl-X (Apoptosis Marker)(BCL2L1/2406), CF405S conjugate
CAT:
37-BNC042406-500
Size:
500 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-Bcl-X (Apoptosis Marker)(BCL2L1/2406), CF405S conjugate
- Description: Bcl-x belongs to the Bcl-2 family of proteins and plays a crucial role in apoptosis. Bcl-X has two isoforms: Bcl-XL (long), a 26 kDa protein which suppresses cell death, and Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2 and promotes apoptosis. This MAb reacts with both Bcl-XS and Bcl-XL proteins, and shows no cross-reaction with Bcl-2 or Bax proteins.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Synonyms: Bcl-x; Bcl-2-like protein 1; BCL2L1; Apoptosis regulator Bcl-X
- CAS Number: 9007-83-4
- UNSPSC: 41116161
- UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
- Gene Name: BCL2L1
- Gene ID: 598
- NCBI Gene ID: 516966
- UniProt: Q07817
- Cellular Locus: Cytoplasmic|Endoplasmic reticulum|Mitochondria
- Host: Mouse
- Species Reactivity: Human
- Immunogen: Recombinant human BCL2L1 protein fragment (around aa 1-135) (exact sequence is proprietary)
- Target Antigen: Bcl-x
- Clonality: Monoclonal
- Isotype: IgG
- Clone: BCL2L1/2406
- Conjugation: CF405S
- Source: Animal
- Applications: IHC, FFPE (verified)
- Validated Applications: IHC, FFPE
- Field of Research: Apoptosis, Cancer
- Positive Control: Jurkat, K562, HL-60, or HeLa Cells. Reed-Sternberg cells in Hodgkin's lymphoma.
- Concentration: 0.1 mg/mL
- Buffer: PBS, 0.1% BSA, 0.05% azide
- Molecular Weight: 27 kDa
- Additionnal Information: ELISA: For coating use Ab at 1-5 ug/mL, order Ab without BSA; Optimal dilution for a specific application should be determined.|Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody
- Shipping Conditions: Room temperature
- Storage Conditions: 4°C; Protect from light; Stable at room temperature or 37°C (98°F) for 7 days.
- Shelf Life: 2 years