CD80/B7-1 Recombinant Mouse Monoclonal Antibody [8-E5-R]

CD80/B7-1 Recombinant Mouse Monoclonal Antibody [8-E5-R]

• Description: CD80/B7-1 is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. After engagement of T-cell receptor with antigen in association with major histocompatibility complex class II, a second signal mediated through the binding of B7 to CD28 greatly upregulates the production of multiple lymphokines. B7-1 is a costimulatory molecule for the activation of both CD4+ and CD8+ T lymphocytes that prevents the induction of clonal anergy. Thus, the transfer of B7-1 genes into tumor cells can induce protective immunity and lead to tumor rejection of some tumors in model systems of in vivo tumor growth.
• Product Name Alternative: Activation B7-1 antigen antibody B lymphocyte activation antigen B7 antibody B7 antibody B7-1 antibody B7-1 antigen antibody B7.1 antibody BB1 antibody CD28 antigen ligand 1 antibody CD28LG antibody CD28LG1 antibody CD80 antibody CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody CD80 antigen antibody CD80 molecule antibody CD80_HUMAN antibody Costimulatory factor CD80 antibody costimulatory molecule variant IgV-CD80 antibody CTLA-4 counter-receptor B7.1 antibody LAB7 antibody T-lymphocyte activation antigen CD80 antibody
• Abbreviation: CD80, CD28LG, CD28LG1, LAB7
• CAS Number: 9000-83-3
• Swiss Prot: P33681 Human
• Cellular Locus: Membrane.
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Synthetic peptide within human CD80 aa 74-118 / 288.
• Isotype: IgG1
• Clone: 8-E5-R
• Conjugation: Non-conjugated
• Type: Recombinant Mouse monoclonal Antibody
• Applications: WB
• Positive Control: Human brain tissue lysates.
• Concentration: 1 mg/mL
• Dilution: WB: 1:1,000
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 33 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
• Recombinant Antibody: Yes