C10orf58 Mouse Monoclonal Antibody [7-B7]

C10orf58 Mouse Monoclonal Antibody [7-B7]

• Description: FAM213A, also known as PAMM (peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) or C10orf58, is a 229 amino acid cytoplasmic protein that belongs to the peroxiredoxin-like FAM213 family and FAM213A subfamily. FAM213A involved in redox regulation of the cell. Acts as an antioxidant. Inhibits TNFSF11-induced NFKB1 and JUN activation and osteoclast differentiation. May affect bone resorption and help to maintain bone mass. Acts as a negative regulator of macrophage-mediated inflammation by inhibiting macrophage production of inflammatory cytokines, probably through suppression of the MAPK signaling pathway.
• Product Name Alternative: C10orf58 antibody CJ058_HUMAN antibody UPF0765 protein C10orf58 antibody
• Abbreviation: Protein PAMM, FAM213A, C10orf58, PAMM, PRO2290, PSEC0139, UNQ611/PRO1198
• CAS Number: 9007-83-4
• Swiss Prot: Q9BRX8 Human
• Cellular Locus: Cytoplasm, Secreted.
• Host: Mouse
• Species Reactivity: Human
• Immunogen: Recombinant protein within Human C10orf58 aa 1-229 / 229.
• Isotype: IgG2a
• Conjugation: Non-conjugated
• Type: Mouse monoclonal Antibody
• Applications: WB, IF-Cell
• Positive Control: Recombinant protein, human skin tissue lysate, HepG2, HUVEC, PC-3M.
• Concentration: 2 mg/mL
• Dilution: WB: 1:500;IF-Cell: 1:50-1:200
• Purity: Protein A affinity purified.
• Form: Liquid
• Buffer: 1*PBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
• Molecular Weight: Predicted band size: 26 kDa
• Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Recombinant Antibody: No