(S)-Mevalonic acid

(S)-Mevalonic acid

• CAS Number: 32451-23-3
• UNSPSC Description: (S)-Mevalonic acid is the isomer of Mevalonic acid (HY-113071). Mevalonic acid ((S)-DCIT) is a precursor substance of the mevalonate pathway，which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure[1][2].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease; Neurological Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/s-mevalonic-acid.html
• Smiles: O=C(O)C[C@@](C)(O)CCO
• Molecular Weight: 148.16
• References & Citations: [1]Moschetti A, et al. Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes. Nanomedicine. 2021 Oct;37:102439. |[2]Soma MR, et al. Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicol Lett. 1992 Dec;64-65 Spec No:1-15.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported