Mevalonic acid
CAT:
804-HY-113071-03
Size:
5 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Mevalonic acid
- CAS Number: 150-97-0
- UNSPSC Description: Mevalonic acid (MVA) is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid can be used in studies of myopathy and heart failure[1][2].
- Target Antigen: Endogenous Metabolite
- Type: Natural Products
- Related Pathways: Metabolic Enzyme/Protease
- Field of Research: Metabolic Disease; Neurological Disease; Cardiovascular Disease; Cancer
- Assay Protocol: https://www.medchemexpress.com/Mevalonic_acid.html
- Purity: 99.0
- Solubility: 10 mM in DMSO
- Smiles: O=C(O)CC(C)(O)CCO
- Molecular Weight: 148.16
- References & Citations: [1]Moschetti A, et al. Coenzyme Q nanodisks counteract the effect of statins on C2C12 myotubes. Nanomedicine. 2021 Oct;37:102439. |[2]Soma MR, et al. Cholesterol and mevalonic acid modulation in cell metabolism and multiplication. Toxicol Lett. 1992 Dec;64-65 Spec No:1-15.Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.|Biomedicines. 2022, 10(10), 2489.|Drugs R D. 2023 Oct 17.|Acta Pharm Sin B. 2023 Apr 17.|Acta Pharmacol Sin. 2021 Feb 19.|Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Aug 16;159217.|Cell Biosci. 2021 Oct 9;11(1):179.|Life Sci Alliance. 2022 Jan 4;5(3):e202101256.|Nature. 2024 Dec 18.
- Shipping Conditions: Room Temperature
- Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
- Clinical Information: Phase 3