Survivin Antibody / BIRC5

Survivin Antibody / BIRC5

• Description: Survivin, also called BIRC5, is a protein encoded by the human BIRC5 gene. It is a member of the IAP (inhibitor of apoptosis family. Survivin binds to the active form of Caspase-3 and -7, effector or executioner caspases, preventing them from continuing the apoptosis-signaling cascade. Expression is regulated by p53, a regulator of apoptosis-control genes which interacts with the Survivin gene promoter region to repress its expression at the mRNA and protein level.
• CAS Number: 9007-83-4
• Host: Rabbit
• Immunogen: A recombinant protein fragment from human Survivin was used as the immunogen for this antibody.
• Clonality: Polyclonal
• Isotype: IgG
• Applications: WB
• Format: Purified
• Buffer: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Reconstitution: Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
• Limitations: This Survivin antibody is available for research use only.