L-Kynurenine (Standard)

L-Kynurenine (Standard)

• CAS Number: 2922-83-0
• UNSPSC Description: L-Kynurenine (Standard) is the analytical standard of L-Kynurenine. This product is intended for research and analytical applications. L-Kynurenine is a metabolite of the amino acid L-tryptophan. L-Kynurenine is an aryl hydrocarbon receptor agonist.
• Target Antigen: Aryl Hydrocarbon Receptor; Endogenous Metabolite
• Type: Reference Standards
• Related Pathways: Immunology/Inflammation;Metabolic Enzyme/Protease
• Field of Research: Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
• Assay Protocol: https://www.medchemexpress.com/l-kynurenine-standard.html
• Smiles: O=C(O)[C@@H](N)CC(C1=CC=CC=C1N)=O
• Molecular Weight: 208.21
• References & Citations: [1]Moyer BJ, et al. Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. Toxicol Appl Pharmacol. 2016 Jun 1;300:13-24.|[2]Sakakibara K, et al. Kynurenine causes vasodilation and hypotension induced by activation of KCNQ-encoded voltage-dependent K(+) channels. J Pharmacol Sci. 2015 Sep;129(1):31-7.|[3]Nozaki K, et al. Neuroprotective effects of L-kynurenine on hypoxia-ischemia and NMDA lesions in neonatal rats. J Cereb Blood Flow Metab. 1992 May;12(3):400-7.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported