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Mefenamic acid-d4

CAT:
804-HY-B0574S-01
Size:
1 mg
Price:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Mefenamic acid-d4 - image 1

Mefenamic acid-d4

  • CAS Number: 1216745-79-7
  • UNSPSC Description: Mefenamic acid-d4 is a deuterium labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively[1][2].
  • Target Antigen: COX
  • Type: Isotope-Labeled Compounds
  • Related Pathways: Immunology/Inflammation
  • Applications: COVID-19-immunoregulation
  • Field of Research: Inflammation/Immunology
  • Purity: 98.0
  • Solubility: 10 mM in DMSO
  • Smiles: O=C(O)C1=C(NC2=CC=CC(C)=C2C)C([2H])=C([2H])C([2H])=C1[2H]
  • Molecular Weight: 245.31
  • References & Citations: [1]Gierse JK, et al. Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase. Biochem J. 1995 Jan 15;305 (Pt 2):479-84.|[2]Hashemipour MA, et al. In Vitro Cytotoxic Effects of Celecoxib, Mefenamic Acid, Aspirin and Indometacin on Several Cells Lines. J Dent (Shiraz). 2016 Sep;17(3):219-25.
  • Shipping Conditions: Blue Ice
  • Storage Conditions: -20°C, 3 years (Powder)
  • Clinical Information: No Development Reported