Mefenamic acid-d4

Mefenamic acid-d4

• CAS Number: 1216745-79-7
• UNSPSC Description: Mefenamic acid-d4 is a deuterium labeled Mefenamic acid. Mefenamic acid is a non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM for hCOX-1 and hCOX-2, respectively[1][2].
• Target Antigen: COX
• Type: Isotope-Labeled Compounds
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Purity: 98.0
• Solubility: 10 mM in DMSO
• Smiles: O=C(O)C1=C(NC2=CC=CC(C)=C2C)C([2H])=C([2H])C([2H])=C1[2H]
• Molecular Weight: 245.31
• References & Citations: [1]Gierse JK, et al. Expression and selective inhibition of the constitutive and inducible forms of human cyclo-oxygenase. Biochem J. 1995 Jan 15;305 (Pt 2):479-84.|[2]Hashemipour MA, et al. In Vitro Cytotoxic Effects of Celecoxib, Mefenamic Acid, Aspirin and Indometacin on Several Cells Lines. J Dent (Shiraz). 2016 Sep;17(3):219-25.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C, 3 years (Powder)
• Clinical Information: No Development Reported