NMDAR antagonist 2
CAT:
804-HY-168240
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
NMDAR antagonist 2
- UNSPSC Description: NMDAR antagonist 2 (compound 3I) is a CNS penetrant NMDAR antagonist with the IC50 of 4.42 μM and 214.75 μM for hGluN1/hGluN2A at −60 mV or 40 mV membrane potentials, respectively. NMDAR antagonist 2 can reduce hippocampal damage[1].
- Target Antigen: iGluR
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: Neuroscience-Neurodegeneration
- Field of Research: Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/nmdar-antagonist-2.html
- Smiles: OCCNC1C2=CC=CC=C2CCC3=CC=CC=C13.Cl
- Molecular Weight: 289.80
- References & Citations: [1]Konecny J, et al. Dizocilpine derivatives as neuroprotective NMDA receptor antagonists without psychomimetic side effects. Eur J Med Chem. 2024;280:116981.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported