GluN2B-NMDAR antagonist-1
CAT:
804-HY-149967-05
Size:
50 mg
Price:
Ask
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
GluN2B-NMDAR antagonist-1
- CAS Number: 3043727-74-5
- UNSPSC Description: GluN2B-NMDAR antagonist-1 is an orally active GluN2B-NMDAR antagonist. GluN2B-NMDAR antagonist-1 has neuroprotective activity. GluN2B-NMDAR antagonist-1 can be used for research of ischemic injury[1].
- Target Antigen: iGluR
- Type: Reference compound
- Related Pathways: Membrane Transporter/Ion Channel;Neuronal Signaling
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology; Neurological Disease
- Assay Protocol: https://www.medchemexpress.com/glun2b-nmdar-antagonist-1.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: O=C(NCCC1=CN(C2=CC=CC=C12)CC3=CC(Br)=CC=C3)/C=C/C4=CC=C(C=C4)O
- Molecular Weight: 475.38
- References & Citations: [1]Quan J,et al. Discovery of novel tryptamine derivatives as GluN2B subunit-containing NMDA receptor antagonists via pharmacophore-merging strategy with orally available therapeutic effect of cerebral ischemia. Eur J Med Chem. 2023 May 5;253:115318.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported