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(R)-JAK2/STAT3-IN-1

CAT:
804-HY-167839
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
(R)-JAK2/STAT3-IN-1 - image 1

(R)-JAK2/STAT3-IN-1

  • CAS Number: 2485758-49-2
  • UNSPSC Description: (R)-JAK2/STAT3-IN-1 is a GP130 D1 domain inhibitor with anti-tumor activity. (R)-JAK2/STAT3-IN-1 can inhibit the phosphorylation of JAK2 and STAT3. The affinity of (R)-JAK2/STAT3-IN-1 for GP130 protein is 3.8 μM. (R)-JAK2/STAT3-IN-1 effectively inhibits the viability and migration of tumor cells and promotes apoptosis[1].
  • Target Antigen: Apoptosis
  • Type: Reference compound
  • Related Pathways: Apoptosis
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/r-jak2-stat3-in-1.html
  • Smiles: NC(N1[C@H](CC(C2=CC=C(C=C2)C(F)(F)F)=N1)C(C3=C4)=CN(CC5=CC=C(C=C5)OCCN6CCCCCC6)C3=CC=C4Br)=O
  • Molecular Weight: 682.57
  • References & Citations: [1]Discovery of bazedoxifene analogues targeting glycoprotein 130
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported