(R)-JAK2/STAT3-IN-1
CAT:
804-HY-167839
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(R)-JAK2/STAT3-IN-1
- CAS Number: 2485758-49-2
- UNSPSC Description: (R)-JAK2/STAT3-IN-1 is a GP130 D1 domain inhibitor with anti-tumor activity. (R)-JAK2/STAT3-IN-1 can inhibit the phosphorylation of JAK2 and STAT3. The affinity of (R)-JAK2/STAT3-IN-1 for GP130 protein is 3.8 μM. (R)-JAK2/STAT3-IN-1 effectively inhibits the viability and migration of tumor cells and promotes apoptosis[1].
- Target Antigen: Apoptosis
- Type: Reference compound
- Related Pathways: Apoptosis
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/r-jak2-stat3-in-1.html
- Smiles: NC(N1[C@H](CC(C2=CC=C(C=C2)C(F)(F)F)=N1)C(C3=C4)=CN(CC5=CC=C(C=C5)OCCN6CCCCCC6)C3=CC=C4Br)=O
- Molecular Weight: 682.57
- References & Citations: [1]Discovery of bazedoxifene analogues targeting glycoprotein 130
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported