JAK2/STAT3-IN-1
CAT:
804-HY-131194
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JAK2/STAT3-IN-1
- CAS Number: 2485758-50-5
- UNSPSC Description: JAK2/STAT3-IN-1 (compound (S)-10a) is a potent GP130 inhibitor with an IC50 of 3.04 µM. JAK2/STAT3-IN-1 shows anti-tumor activity[1].
- Target Antigen: Interleukin Related
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/jak2-stat3-in-1.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(N1N=C(C2=CC=C(C(F)(F)F)C=C2)C[C@H]1C3=CN(CC4=CC=C(OCCN5CCCCCC5)C=C4)C6=C3C=C(Br)C=C6)N
- Molecular Weight: 682.57
- References & Citations: [1]Song D, et al. Discovery of bazedoxifene analogues targeting glycoprotein 130. Eur J Med Chem. 2020 Aug 1;199:112375.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported