Human PD-L1 inhibitor IV

Human PD-L1 inhibitor IV

• CAS Number: 2135542-83-3
• UNSPSC Description: Human PD-L1 inhibitor IV, a polypeptide, is a competitive human PD-1 protein inhibitor with a Kd value of 1.38 μM. Human PD-L1 inhibitor IV inhibits the interaction of hPD-1/hPD-L1[1].
• Target Antigen: PD-1/PD-L1
• Type: Peptides
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/human-pd-l1-inhibitor-iv.html
• Purity: 99.68
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](CC(N)=O)C(N[C@H](C(O)=O)CCC(N)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(N)=O)NC(CN)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O
• Molecular Weight: 1856.90
• References & Citations: [1]Qiao Li, et al. Discovery of peptide inhibitors targeting human programmed death 1 (PD-1) receptor. Oncotarget. 2016 Oct 4;7(40):64967-64976.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported