Human PD-L1 inhibitor I

Human PD-L1 inhibitor I

• CAS Number: 2135542-86-6
• UNSPSC Description: Human PD-L1 inhibitor I is a hPD-1 peptide ligand, with a KD of 3.39 μM. Human PD-L1 inhibitor I may disturb the binding of hPD-L1 to hPD-1[1].
• Target Antigen: PD-1/PD-L1
• Type: Peptides
• Related Pathways: Immunology/Inflammation
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/human-pd-l1-inhibitor-i.html
• Purity: 98.93
• Solubility: 10 mM in DMSO
• Smiles: OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)CC(C)C)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O)=O)NC([C@H](CC(O)=O)NC([C@@H](NC([C@H](CC(N)=O)NC([C@@H](N)CC5=CC=CC=C5)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O
• Molecular Weight: 2350.58
• References & Citations: [1]Tianyu Wang, et al. Development of Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Signaling Pathway. J Med Chem. 2019 Feb 28;62(4):1715-1730.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
• Clinical Information: No Development Reported