(S)-Rasagiline mesylate

(S)-Rasagiline mesylate

• CAS Number: 202464-88-8
• UNSPSC Description: (S)-Rasagiline (TVP1022) mesylate is the relatively inactive S-enantiomer form of Rasagiline mesylate. Rasagiline mesylate is a highly potent selective irreversible MAO inhibitor with IC50s of 4.43 nM and 412 nM for rat brain MAO B and A activity, respectively[1]. (S)-Rasagiline mesylate is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: Monoamine Oxidase
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/TVP1022-mesylate.html
• Solubility: 10 mM in DMSO
• Smiles: C#CCN[C@H]1CCC2=CC=CC=C21.OS(=O)(C)=O
• Molecular Weight: 267.34
• References & Citations: [1]M B Youdim, et al. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol. 2001 Jan;132(2):500-6.
• Shipping Conditions: Room temperature
• Clinical Information: Launched