Rasagiline (mesylate) (Standard)

Rasagiline (mesylate) (Standard)

• CAS Number: 161735-79-1
• UNSPSC Description: Rasagiline (mesylate) (Standard) is the analytical standard of Rasagiline (mesylate). This product is intended for research and analytical applications. Rasagiline (R-AGN1135) mesylate is a highly potent selective irreversible mitochondrial monoamine oxidase (MAO) inhibitor with IC50s of 4.43?nM and 412?nM for rat brain MAO B and A activity, respectively[1]. Rasagiline (mesylate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: Apoptosis; Autophagy; Monoamine Oxidase
• Type: Reference Standards
• Related Pathways: Apoptosis;Autophagy;Neuronal Signaling
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/rasagiline-mesylate-standard.html
• Smiles: CS(=O)(O)=O.C#CCN[C@H]1C2=CC=CC=C2CC1
• Molecular Weight: 267.34
• References & Citations: [1]M B Youdim, et al. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol. 2001 Jan;132(2):500-6.|[2]Nadia Stefanova, et al. Rasagiline is neuroprotective in a transgenic model of multiple system atrophy. Exp Neurol. 2008 Apr;210(2):421-7.|[3]Shawna Tazik, et al. Comparative neuroprotective effects of Rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis. Neurotox Res. 2009 Apr;15(3):284-90.
• Shipping Conditions: Room temperature