Anti-GRK6 Antibody
CAT:
519-A03623
Size:
100 µL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-GRK6 Antibody
- Background: Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis By similarity. Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor: LRP6 during Wnt signaling (in vitro).
Benovic J.L., J. Biol. Chem. 268:19521-19527(1993).
Haribabu B., Proc. Natl. Acad. Sci. U.S.A. 90:9398-9402(1993).
Stoffel R.H., J. Biol. Chem. 269:27791-27794(1994). - Description: Boster Bio Anti-GRK6 Antibody (Catalog # A03623). Tested in WB, IF applications. This antibody reacts with Human, Mouse, Rat.
- Synonyms: G protein-coupled receptor kinase 6;2.7.11.16;G protein-coupled receptor kinase GRK6;GRK6;GPRK6;
- CAS Number: 9007-83-4
- Gene Name: GRK6
- UniProt: P43250
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Immunogen: Synthesized peptide derived from N-terminal of human GRK6.
- Clonality: Polyclonal
- Applications: WB, IF
- Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Form: Liquid
- Molecular Weight: 65991 MW
- Components: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Storage Conditions: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.