Anti-GRK6 Antibody
CAT:
519-A03623-1
Size:
0.1 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Anti-GRK6 Antibody
- Background: The G protein–coupled receptor kinases (GRKs) are a versatile family of kinases that play a critical role in cancer metastasis through their regulation of G-protein coupled receptors (GPCRs) involved in growth factor mediated cell migration (1, 2). Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state (1). GRK6 is one of 7 members of the GRK serine/threonine kinase subfamily, which has been shown to modulate the Wnt signaling pathway via phosphorylation of LRP6 (3, 4), and the insulin-like growth factor signaling pathway (4). GRK6 may also play a role in immune system function (5).
- Description: Boster Bio Anti-GRK6 Antibody (Catalog # A03623-1). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
- Synonyms: GPRK6, GPRK6, G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6
- CAS Number: 9007-83-4
- Gene Name: GRK6
- UniProt: P43250
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Cross Reactivity: GRK6 antibody is human, mouse and rat reactive. Multiple isoforms of GRK6 are known to exist. This antibody is predicted to not cross-react with other members of the GRK protein family.
- Immunogen: GRK6 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human GRK6. The immunogen is located within the last 50 amino acids of GRK6.
- Clonality: Polyclonal
- Applications: ELISA, WB, IHC-P, IF
- Purification: GRK6 antibody is affinity chromatography purified via peptide column.
- Concentration: 1 mg/mL
- Form: Liquid
- Molecular Weight: 65991 MW
- Components: GRK6 antibody is supplied in PBS containing 0.02% sodium azide.
- Storage Conditions: GRK6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
- Fragment: IgG