α-Amylase/α-Glucosidase-IN-6

α-Amylase/α-Glucosidase-IN-6

• UNSPSC Description: α-Amylase/α-Glucosidase-IN-6 (compound 5j) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50s of 17.0 and 40.1 µM, respectively. α-Amylase/α-Glucosidase-IN-6 exhibits anti-hyperglycemic activities[1].
• Target Antigen: Amylases; Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-amylase-α-glucosidase-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: ClC1=CC=CC=C1C2=NOC(COC3=NC4=CC=C(OC)C=C4N=C3NCC)=C2
• Molecular Weight: 410.85
• References & Citations: [1]Phongphane L, et, al. Synthesis, biological evaluation, and molecular modelling of novel quinoxaline-isoxazole hybrid as anti-hyperglycemic. Comput Biol Chem. 2023 Oct:106:107938.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported