α-Amylase/α-Glucosidase-IN-1

α-Amylase/α-Glucosidase-IN-1

• CAS Number: 329783-03-1
• UNSPSC Description: α-Amylase/α-Glucosidase-IN-1 (compound 33) is a potent α-amylase/α-glucosidase inhibitor with IC50s of 2.01, 2.09 µM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucosidase-IN-1 has the potential of anti hyperglycemia[1].
• Target Antigen: Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-amylase-α-glucosidase-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: C12=C(NC(/C=N/N3C=NN=C3)=C2)C=CC=C1
• Molecular Weight: 211.22
• References & Citations: [1]Yeye EO,et al. Syntheses, in vitro α-amylase and α-glucosidase dual inhibitory activities of 4-amino-1,2,4-triazole derivatives their molecular docking and kinetic studies. Bioorg Med Chem. 2020 Jun 1;28(11):115467.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported