Mcl-1 inhibitor 13

Mcl-1 inhibitor 13

• CAS Number: 2445466-06-6
• UNSPSC Description: Mcl-1 inhibitor 13 (Example 9) is a MCL-1 inhibitor (Ki: 8.2 nM). Mcl-1 inhibitor 13 can be used for the research of cancers[1].
• Target Antigen: Bcl-2 Family
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mcl-1-inhibitor-13.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC=CC=C1C2=NC(COC3=C(C[C@H](C(O)=O)OC4=NC=NN5C4=[C@@]([C@@]6=C(C)C(Cl)=C(OCCN7CCN(C)CC7)C=C6)C(C8=CC=C(F)C=C8)=C5)C=CC=C3)=CC=N2
• Molecular Weight: 858.35
• References & Citations: [1]Jincong Zhuo, et al. 2-((5-(phenyl)-pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)-3-(phenyl)propanoic acid derivatives and related compounds as mcl-1 enzyme inhibitors for treating cancer. Patent WO2020123994.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported