2′-Deoxy-N-(2-furanylmethyl)guanosine

2′-Deoxy-N-(2-furanylmethyl)guanosine

• CAS Number: 1227069-12-6
• UNSPSC Description: 2′-Deoxy-N-(2-furanylmethyl)guanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-n-2-furanylmethyl-guanosine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1C[C@H](N2C(N=C(NCC3=CC=CO3)NC4=O)=C4N=C2)O[C@@H]1CO
• Molecular Weight: 347.33
• References & Citations: [1]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported