2’-Deoxy-N2-cyclopentyl guanosine

2’-Deoxy-N2-cyclopentyl guanosine

• CAS Number: 1353757-90-0
• UNSPSC Description: 2’-Deoxy-N2-cyclopentyl guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-n2-cyclopentyl-guanosine.html
• Solubility: 10 mM in DMSO
• Smiles: OC[C@@H]1[C@@H](O)C[C@H](N2C(N=C(NC3CCCC3)NC4=O)=C4N=C2)O1
• Molecular Weight: 335.36
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported