2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite
CAT:
804-HY-152979
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite
- CAS Number: 176755-87-6
- UNSPSC Description: 2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].
- Target Antigen: DNA/RNA Synthesis
- Type: Oligonucleotides
- Related Pathways: Cell Cycle/DNA Damage
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/2-deoxy-5-o-dmt-n4-fmoc-5-methylcytidine-3-ce-phosphoramidite.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1N=C(NC(OCC2C3=C(C=CC=C3)C4=C2C=CC=C4)=O)C(C)=CN1[C@H]5C[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C6=CC=CC=C6)(C7=CC=C(OC)C=C7)C8=CC=C(OC)C=C8)O5
- Molecular Weight: 966.07
- References & Citations: [1]Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported