FBPase-IN-2
CAT:
804-HY-147645
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
FBPase-IN-2
- CAS Number: 127143-25-3
- UNSPSC Description: FBPase-IN-2 (HS36) is a potent Fructose-1,6-bisphosphatase (FBPase) covalent inhibitor with an IC50 of 0.15 μM. FBPase-IN-2 reduces glucose production in hepatocytes. FBPase-IN-2 can be used for type 2 diabetes mellitus research[1].
- Target Antigen: FBPase
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Metabolic Disease
- Assay Protocol: https://www.medchemexpress.com/fbpase-in-2.html
- Solubility: 10 mM in DMSO
- Smiles: O=[N+](C1=CC=C(C=C1)/C=C([N+]([O-])=O)\Cl)[O-]
- Molecular Weight: 228.59
- References & Citations: [1]Han X, et al. Biological evaluation and SAR analysis of novel covalent inhibitors against fructose-1,6-bisphosphatase. Bioorg Med Chem. 2020 Sep 15;28(18):115624.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported