FBPase-IN-3

FBPase-IN-3

• UNSPSC Description: FBPase-IN-3 (compound 45) is a FBPase (fructose-1,6-bisphosphatase) inhibitor with an IC50 of 2.08 μM. FBPase-IN-3 exhibits potent inhibitory activity of gluconeogenesis[1].
• Target Antigen: FBPase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/fbpase-in-3.html
• Smiles: O=C(NS(=O)(C1=CC=C(OC)C=C1)=O)C2=CC(Cl)=CC(C3=NC4=CC=CC=C4N3)=C2
• Molecular Weight: 441.89
• References & Citations: [1]Huahao Wang, et al. Discovery of novel fructose-1,6-bisphosphatase inhibitors bearing benzimidazole scaffold using a dual-ligand molecular docking model. Eur J Med Chem. 2024 Sep 19:279:116888.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported