CDK2-IN-23
CAT:
804-HY-162255-06
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CDK2-IN-23
- CAS Number: 2488073-20-5
- UNSPSC Description: CDK2-IN-23 (Compound 17) is a kinase selective and highly potent CDK2 inhibitor (IC50 = 0.29 nM). CDK2-IN-23 shows the pharmacodynamic inhibition of CDK2 in CCNE1-amplified mouse models. CDK2-IN-23 can be used for the research of cancer[1].
- Target Antigen: CDK
- Type: Reference compound
- Related Pathways: Cell Cycle/DNA Damage
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/cdk2-in-23.html
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: CC(O)(CN1C=C(C2=C(C(F)(F)F)C=NC(NC3CCN(S(=O)(C4CC4)=O)CC3)=N2)C=N1)C
- Molecular Weight: 488.53
- References & Citations: [1]Hummel JR, et al. Discovery of (4-Pyrazolyl)-2-aminopyrimidines as Potent and Selective Inhibitors of Cyclin-Dependent Kinase 2. J Med Chem. 2024 Feb 22;67(4):3112-3126.
- Shipping Conditions: Blue Ice
- Clinical Information: No Development Reported